ALDEHYDE DEHYDROGENASE 2 PROTECTS AGAINST POST-CARDIAC ARREST MYOCARDIAL DYSFUNCTION THROUGH A NOVEL MECHANISM OF SUPPRESSING MITOCHONDRIAL REACTIVE OXYGEN SPECIES PRODUCTION

Post-cardiac arrest myocardial dysfunction significantly contributes to early mortality after the return of spontaneous circulation.However, no effective therapy is available now.Aldehyde dehydrogenase 2 (ALDH2) enzyme has been shown to protect the heart from aldehyde toxicity such as 4-hydroxy-2-nonenal (4-HNE) and oxidative stress.In this study,

The Nipah virus (NiV) infection is one of the newly emerging deadly zoonotic diseases which carries a significant weightage of Artisan Globe mortality among its victims.Due to the relatively recent history of its emergence and only a few known outbreaks, we cannot predict but foresee its potential to create havoc, which can be far more dreadful tha

The Arab Spring uprisings have released a flood of land and property Notepads conflicts, brought about by decades of autocratic rule.Expropriations, corruption, poor performance of the rule of law, patronage and sectarian discrimination built up a wide variety of land and property transgressions over approximately 30 years.The result has been the c

Abstract.The ant genus Myrmoxenus consists of about ten socially parasitic species including active slave-makers and workerless "degenerate slave-makers".Myrmoxenus tamarae was previously known only from type material, two Notepads workers collected at Daba, Georgia and nothing was known about its life history, colony structure or the morphology of

Introduction Approximately 10 300 people are diagnosed with pancreatic cancer each year in the UK.The cancer and its treatment inflict a significant physical, functional and emotional burden on patients.Research suggests that patients have many ongoing needs for support and care, but that these needs are not met by existing services.Family members